International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 3, Issue 4 | Case Report | Open Access DOI
Yoalkris Elizabeth Salcedo*
Paria Remolina1, Yoalkris Elizabeth Salcedo2*, Ángel Creciano Mendoza Barrera3, Walid Ali Malik Rodriguez3, Madelin Reynoso Ruiz4 and Maritza Ramírez Natera4
1Medical Student at Universidad Nacional Pedro Henríquez Ureña, Dominican Republic
2Medical Student at Universidad Iberoamericana, Dominican Republic
3Medical Student at Universidad Nacional Pedro Henríquez Ureña, Dominican Republic
4Pediatric Infectious Disease at Hospital Infantil Dr. Robert Reid Cabral, Dominican Republic
*Correspondence to: Yoalkris Elizabeth Salcedo
Fulltext PDFThis case report details the presentation, treatment, and clinical course of an 8-year-old boy with epilepsy who developed Stevens-Johnson syndrome (SJS) following an adjustment in his anticonvulsant regimen. The patient, from Los Guaricanos, Dominican Republic, was admitted to Hospital Dr. Robert Reid Cabral after reducing the dose of levetiracetam to 500 mg and increasing the dose of lamotrigine to 25 mg. Upon admission, the patient presentedmaculo-papular erythema, accompanied by facial edema, lip swelling, and lesions that later formed pustules and scabs, on the face, neck and chest with mucocutaneous manifestations, conjunctival injection. Given the suspicion of SJS, multidisciplinary interventions were initiated. During the subsequent days management led to notable clinical improvement. However, on the fifth day, he had three tonic-clonic seizures, necessitating a neurological reevaluation and anticonvulsant adjustment. This case highlights the importance of recognizing and managing rare adverse drug reactions such as SJS in pediatric patients with epilepsy.
Steven-Johnson syndrome; Lamotrigine; Levetiracetam; Epilepsy; Drug reaction
Remolina P, Salcedo YE, Barrera ACM, Rodriguez WAM, Ruiz MR, Natera MR. A Case Report of Steven Johnson Syndrome in the Dominican Republic. Int Clinc Med Case Rep Jour. 2024;3(4):1-8.