Annals of Case Reports and Clinical Studies (ISSN: 2834-5673) | Volume 1, Issue 1 | Research Article | Open Access
Mehdi Karasu*
Department of Cardiology, Zilan Hospital, Turkey
*Correspondence to: Mehdi Karasu
Fulltext PDF1.1. Objective: Gestational Diabetes Mellitus (GDM) is associated with premature cardiovascular disease and adverse cardiovascular outcomes in the mother. Subclinical cardiac functional changes in the left ventricle have been reported during pregnancy using conventional echocardiography but results are inconsistent. The aim of this study is to determine whether there is deterioration in cardiac functions and cardiac structure during pregnancy in patients with gestational diabetes compared to normal pregnancies, and thus to provide a chance for early intervention.
1.2. Methods: A total of 60 pregnant patients, 30 of whom had gestational diabetes and 30 of whom did not have gestational diabetes, were included in the study. Diagnosis of GDM was made by performing the two-step approach recommended by National Institute for Health and Care Excellence (NICE) guidelines. The protocol included standard parasternal and apical views as per American Society of Echocardiography (EAE/ASE) guidelines. Height, weight, gestational age, gestational week, blood pressure, heart rate information were recorded.
1.3. Results: In the GDM group, compared to controls, there were no difference according to maternal age, weight, height, gestastional week, number of gestations and bmi, heart rate and blood pressure. At 20 to 40 weeks' gestation, women with GDM, compared to controls, had no significant difference according to bazal cardiac measurements. There were no statistically significant difference in terms of filling pressures, left and right ventricular mpi, TAPSE, tissue doppler evaluation of left and right ventricule and left and right atrium area.
1.4. Conclusion: At time of pregnancy there is no difference between GDM and non-GDM in terms of cardiac systolic and diastolic parameters and cardiac structure. It is possible that the effects of high plasma glucose on cardiac functions have not been fully elucidated, and studies with different imaging methods and biomarkers are needed in larger patient groups that can exclude the effect of independent variables.
Gestational diabetes; Myocardial performance index; Diastolic functions
Mehdi Karasu, Ozkan Karaca, Şeyda Yavuzkir, Kader Uğur.Gestational Diabetes: A Temporary Condition may Deteriorate Maternal Cardiac Functions and Structure?.Ann Case Rep Clin Stud. 2022;1(1):1-8.