Annals of Case Reports and Clinical Studies (ISSN: 2834-5673) | Volume 5, Issue 6 | Clinical Study | Open Access DOI
Abhinn Miglani*
Abhinn Miglani1*, Upasa Sarma Medhi1,Antara Bhattacharyya2 ,Prasad Dhadse3, Sadaf Fatima Shaikh4
1Department of Oral & Maxillofacial Surgery, Institute Of Dental Sciences, Bhubaneswar, India
2 Department of Oral & Maxillofacial Surgery, Regional Dental College, Guwahati, India
3Department of Periodontics & Implantology, Sharad Pawar Dental College & Hospital, Sawangi(Meghe), Wardha, Maharashtra, India
4Department of Periodontology, M.A.Rangoonwala College of Dental Science and Research centre, Pune, Maharashtra, India
*Correspondence to: Abhinn Miglani
Fulltext PDFBackground: Chronic Kidney Disease (CKD) is a progressive disorder associated with chronic systemic inflammation and various oral manifestations, including periodontal disease. Emerging evidence suggests a bidirectional relationship between CKD and periodontal disease, wherein periodontal inflammation may contribute to systemic inflammatory burden and renal dysfunction.
Aim: To evaluate the periodontal status of patients with Chronic Kidney Disease stages I, II, IIIA, and IIIB and to assess its association with renal function parameters.
Materials and Methods: A cross-sectional observational study was conducted among 60 patients diagnosed with CKD stages I, II, IIIA, and IIIB attending a tertiary care centre. Periodontal status was assessed using Plaque Index (PI), Gingival Index (GI), Periodontal Probing Depth (PPD), and Clinical Attachment Loss (CAL). Renal function was evaluated using estimated glomerular filtration rate (eGFR) and serum creatinine. Correlation analysis was performed using Spearman’s rank correlation coefficient.
Results: Progressive increase in Periodontal Probing Depth and Clinical Attachment Loss were observed with advancing CKD severity. Mean CAL increased from 3.93 ± 0.86 mm in Stage I to 6.26 ± 0.79 mm in Stage IIIB. Significant negative correlations between CAL and eGFR were observed in Stage IIIA (r = −0.45, p = 0.042) and Stage IIIB (r = −0.92, p = 0.0001), indicating worsening periodontal status with declining renal function. Although serum creatinine values demonstrated variability across CKD stages, eGFR-based staging remained consistent and reliable for disease classification.
Conclusion: Patients with CKD exhibited a substantial periodontal disease burden, with periodontal deterioration increasing alongside CKD severity. Significant associations between periodontal attachment loss and declining renal function were observed in advanced CKD stages. These findings emphasize the importance of routine periodontal assessment and preventive oral healthcare as part of comprehensive CKD management.
Chronic Kidney Disease; Periodontal Disease; Clinical Attachment Loss; Periodontal Probing Depth; Estimated Glomerular Filtration Rate; Serum Creatinine; Oral Health
Abhinn Miglani, Upasa Sarma Medhi, Antara Bhattacharyya, Prasad Dhadse, Sadaf Fatima Shaikh. Evaluation of Periodontal Status in Patients with Chronic Kidney Disease in Tertiary Care Centre. Ann Case Rep Clin Stud. 2026;5(5):1-8.