Annals of Case Reports and Clinical Studies (ISSN: 2834-5673) | Volume 3, Issue 1 | Case Report | Open Access
Davaasambuu Enkhmaa*
Dagvadorj B1, Enkhtaivan O2, Myagmartseren P1, Nomuudari O, Purevsuren J3, Enkhmaa D1,2*
1Infertility and Reproductive Center, National Center for Maternal and Child Health, Mongolia
2Research Department, National Center for Maternal and Child Health, Mongolia
3Medical Genetics Laboratory, National Center for Maternal and Child Health, Mongolia
*Correspondence to: Davaasambuu Enkhmaa
Fulltext PDFBackgrounds: Infertility is a common disease that impacts about 20% of couples, with male infertility contributing to roughly half of these cases. Testicular Sperm Extraction (TESE) is the main treatment for male infertility with Non-Obstructive Azoospermia (NOA). Appropriate counseling regarding sperm extraction approaches for infertile couples is crucial to decide further treatments and to expect achievable outcomes.
Aims: Our purpose is to identify potential clinical predictor factors for TESE outcomes.
Material and Methods: The study was conducted prospectively in 2019-2022. We recruited 48 male patients with diagnosis of azoospermia in the Infertility and Reproductive Center, National Center for Maternal and Child health in Mongolia.
Results: Mean age of males were 35.0 ± 5.03 with range of 22-45. Spermatozoa were successfully obtained from 32 (66.7%) men. There was statistically significant higher level of Follicle-Stimulating Hormone (FSH) of 19.7 ± 12.3 (p=0.0007) in the failed sperm retrieval group comparing successful sperm retrieval group. Researchers used receiver operating characteristics curve to determine which FSH threshold level resulted successful retrieval of spermatozoa. Of 58.3% patients with FSH less than 12.4U/L or normal had spermatozoa and 8.3% patients had without spermatozoa. The mean level of FSH in the cases without spermatozoa was 19.7 ± 12.3 IU/L. It was significantly higher than the cases with spermatozoa (p=0.007). FSH level of 12.4 mIU/mL is 90% sensitive to predict 90.0% of spermatozoa retrieval. We carried out 29 embryo transfers which was resulted 31.0% pregnancy.
Conclusion: It is possible to assess the outcome of TESE procedures based on the level of FSH in the serum.
Azoospermia; Sperm retrieval; Testicular sperm extraction
Dagvadorj B, Enkhtaivan O, Myagmartseren P, Nomuudari O, Purevsuren J, Enkhmaa D.Predicting Factors for the Outcome of Testicular Sperm Extraction in Men with Azoospermia.Ann Case RepClinStud.2024;3(1):1-6.