International Journal of Gastroenterology and Hepatology (ISSN: 2995-2301) | Volume 2, Issue 2 | Mini Review | Open Access

Next-Gen Screening Review: The Rise of Capsule Colonoscopy in Colorectal Cancer Screening

Akash Patel MD*

Akash Patel MD1*, Utsav Vaghani MD2, Sarang Tusharbhai Mehta MD3

1Department of Internal Medicine, Eisenhower Medical Centre, Rancho Mirage, California, USA

2Department of Internal Medicine, UNM Children Hospital, Surat, Gujarat, India

3Department of Internal Medicine, Smt. N.H.L. Municipal Medical College, Ahmedabad, Gujarat, India

*Correspondence to: Akash Patel MD 

Fulltext PDF


Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality, particularly affecting individuals below 50 years of age in the U.S. Despite the survival benefits conferred by existing screening methods, challenges such as adherence, sensitivity variability, and procedural risks limit their efficacy. This review explores the advent of capsule colon endoscopy (CCE) as a non-invasive screening alternative, capable of circumventing many limitations of traditional methods. CCE utilizes a swallowable imaging device to wirelessly transmit colonic images, showing promise in enhancing patient experience and adherence through its less invasive nature. Technological advancements have improved image quality, incorporated artificial intelligence for image analysis, and refined capsule design, although challenges in visualization and cost remain. Clinical studies report high sensitivity and specificity of CCE for polyp detection, with improvements in detecting lesions in the right colon. Current guidelines recommend careful patient selection and preparation, with ongoing updates as evidence evolves. Future research is focused on improving diagnostic precision, assessing cost-effectiveness, and integrating CCE into screening programs. With its potential to increase screening adherence and reduce CRC incidence, CCE represents a significant development in the field of gastroenterology, meriting continued exploration and optimization in clinical practice.



Akash Patel MD, Utsav Vaghani MD, Sarang Tusharbhai Mehta.Next-Gen Screening Review: The Rise of Capsule Colonoscopy in Colorectal Cancer Screening. Int Jour Gastro Hepat. 2023;2(2):1-5.