Salient Journal of Cardiology (ISSN 2994-774X) | Volume 2, Issue 1 | Review Article | Open Access

Influence of Syncope on Clinical Outcomes in Acute Pulmonary Embolism: A Systematic Review

Tanveer Singh*

Venkata Sai Harshabhargav Chenna1, Chengala Ananyaa Gowthavaram2, Tanveer Singh3*, Heeya Shah4, Navjot Singh5, Baris Tarimci6,Lokeshwar Raaju Addi Palle7, Madiha D. Haseeb8,Ogbonnaya Akuma9, Pugazhendi Inban10,Chinaza M. Akuma11,Khaja Nayabrasool Syed12,Evgenii Kravchenko13, Sumit Kumar14, Nnesochi Okoroafor15, Ewuradjoa Ayirebi-Acquah16

1Medicine, University of perpetual help system dalta, Las pinas, PHL

2Internal Medicine, Malla Reddy Institute of Medical Sciences, Hyderabad Telangana, Hyderabad , India

3College of Medicine, S.G.R.D. Amritsar, Punjab, India, Punjab, India

4Internal Medicine, Division of Research & Academic Affairs Larkin Community Hospital, South Miami, USA

5Orthopaedics, Global Multispeciality Hospital, Jalandhar, Punjab, Jalandhar, India

6Internal Medicine, Ege University Faculty of Medicine, Izmir, Turkey

7Department of Surgery, Kamala Children's Hospital, Chennai, India, Chennai, India

8Neurology, Dow University of Health Sciences, Karachi, Pakisthan

9Internal Medicine, Ebonyi State University, Abakaliki Nigeria, Abakaliki, NGA

10Department of General Medicine, Government Medical College, Omandurar, Chennai, India

11MPH, Chamberlain University, College of Health Professions, Chicago, USA

12Internship, Narayana Medical College, Nellore, India

13Internal Medicine, N.N. Blokhin NMRCO, Moscow, RUS

14Internal Medicine, Armed Forces Medical College, Pune, India, Pune, India

15Surgery, IMSUTH, Orlu, NGA

16Internal Medicine, Lekma Hospital, Accra, GHA

*Correspondence to: Tanveer Singh 

Fulltext PDF

Abstract

A blood clot in the lungs can cause acute pulmonary embolism (PE), which can cause life-threatening breathing problems, chest pain, and even cardiac arrest. Anyone, regardless of age, gender, or race, can be afflicted by this illness. The incidence of acute PE is rising, which raises serious public health concerns due to the rising prevalence of obesity, smoking, and sedentary lifestyles.[1] Syncope, or fainting, is a common symptom experienced by patients with acute PE. PE is a condition where a blood clot forms in the pulmonary arteries, the blood vessels that carry blood from the heart to the lungs.[2] When this happens, the clot can block blood flow to the lungs, decreasing oxygen levels. Syncope in acute PE is a significant concern, as it can signify sudden and severe hemodynamic compromise caused by large or multiple pulmonary emboli.[3] Syncope can also predict poor outcomes such as 30-day mortality, hemodynamic collapse, and prolonged hospital stay. Risk stratification models such as the Pulmonary Embolism Severity Index (PESI) and the simplified PESI (sPESI) can help healthcare providers identify patients with acute PE at high risk of adverse outcomes.[4] These models evaluate various clinical and laboratory variables, such as age, comorbidities, and biomarkers, to predict the short-term mortality risk in patients with acute PE.  It is typical for individuals with acute PE to present with syncope, and this incidence is thought to be linked to a poor clinical outcome.[5] Understanding the connection between syncope and clinical outcomes in acute PE is obligatory to prevent severe morbidity and mortality and to improve patient prognosis.[6] This review provides a thorough overview of the literature on the impact of syncope on clinical outcomes of PE, outlining the current understanding and possible future study directions.

Keywords:

Pulmonary Embolism; Breathing problems, Chest pain; Cardiac arrest

Citation:

Venkata Sai Harshabhargav Chenna, Chengala Ananyaa Gowthavaram, Tanveer Singh, Heeya Shah, Navjot Singh, Baris Tarimci, Lokeshwar Raaju Addi Palle, et al. Influence of Syncope on Clinical Outcomes in Acute Pulmonary Embolism: A Systematic Review. Sali Jour Cardi. 2023;2(1):1-12.