Annals of Medicine Research and Public Health (ISSN: 2995-5955) | Volume 4, Issue 1 | Case Report | Open Access DOI

Lamotrigine-Induced Rash and Facial Swelling in a 27-Year-Old Female: A Case Report

Saloni^*

Harleen1, Saloni1*, Seth AK1, Navtej Singh2

1Department of Psychiatry, Santosh Medical College and Hospital, Ghaziabad, 201001, India

2Department of Skin, M.H. Jalandhar, 144005, India

^*Correspondence to: Saloni 

Abstract

Lamotrigine, a widely used antiepileptic and mood stabilizer, is associated with a risk of dermatologic hypersensitivity reactions, which can range from mild rashes to severe cutaneous adverse reactions. We report the case of a 27-year-old female with recurrent depressive disorder who developed widespread rash and facial swelling following initiation of Lamonex SR (lamotrigine) 100 mg once daily without titration. Prompt recognition and discontinuation of the drug led to complete resolution of symptoms. This case highlights the importance of careful titration and early monitoring when initiating lamotrigine.

Keywords:

Lamotrigine, drug hypersensitivity, drug-induced rash, facial edema, adverse drug reaction, recurrent depressive disorder

Citation:

Harleen, Saloni, Seth AK, Navtej Singh. Lamotrigine-Induced Rash and Facial Swelling in a 27-Year-Old Female: A Case Report. Ann Med Res Pub Health. 2025;4(1):1-5.