International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 2, Issue 9 | Case Report | Open Access

A Rare and Challenging Case: Infective Endocarditis and Pulmonary Hypertension in A Patient with Alagille Syndrome and Bicuspid Aortic Valve

Ferit Boyuk^*

Department of Cardiology, Health Sciences University, Yedikule Chest Disease and Thoracic Surgery Training And Research Hospital, Turkey

^*Correspondence to: Ferit Boyuk 

Abstract

Alagille syndrome is a genetic disease with multi-organ involvement and can cause various congenital cardiac lesions. This syndrome is caused by mutations in the JAG1 and NOTCH gene pathways. As a result of these lesions, pulmonary hypertension can be seen in patients. While pulmonary hypertension is observed especially due to pulmonary valve stenosis; It may be due to various causes such as tetralogy of Fallot. Currently, pulmonary hypertension has not been reported in Alagille patients without cardiac anomalies in the literature.

Keywords:

Alagille syndrome; Hypertension; Cardiac

Citation:

Gulsum Bingol, Emre Ozmen, Ozge Ozden, Ferit Boyuk, Matteo Cameli. A Rare and Challenging Case: Infective Endocarditis and Pulmonary Hypertension in A Patient with Alagille Syndrome and Bicuspid Aortic Valve.Int Clinc Med Case Rep Jour. 2023;2(9):1-8.