International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 2, Issue 9 | Research Article | Open Access
Do Thị Vinh An*
Hematology and Blood Tranfusion centrer, Bach Mai Hospital, Vietnam
*Correspondence to: Do Thị Vinh AnFulltext PDF
Objective: To identify some common chromosomal mutation in patients with Multiple myeloma(MM)at Bach Mai hospital, from June2016 to June2021.
Methods: We reviewed the cytogenetic results from 363 patients who were diagnosed with MMbyIMWG diagnostic criteria2014 at Bach Mai hospital.
Results: Chromosomal abnormalities were detected in 35,3% (128/363) of the patients. Amongthese results, 128 cases (82,8%) had both numerical and structural chromosome abnormalities.Hyperdiploidy with structural cytogenetic aberrations was the most common finding (42,19%),followedby hypodiploidy with structural aberrations (23,44%).
Themostcommonnumericalabnormalitiesweregainsofchromosomes9 with 28,57%.
Multiple Myeloma; Chromosome
Nguyen Tuan Tung, Nguyen Thanh Binh Minh, Do Thị Vinh An. Abnormal Chromosome in Patients with Multiple Myeloma: A Cohor Study in Vietnam.Int Clinc Med Case Rep Jour. 2023;2(9):1-8.