International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 3, Issue 11 | Case Report | Open Access
Ratika Dogra*
1Department of Internal Medicine, Mercy St Vincent Hospital, Toledo, OH, USA
2Third Year Medical Resident, Department of Internal Medicine, Mercy St Vincent Hospital, Toledo, OH, USA
3Medical Student, Ohio University Heritage College of Osteopathic Medicine, Athens, OH, USA
4Department of Infectious Disease, Mercy St Vincent Hospital, Toledo, OH, USA
*Correspondence to: Ratika Dogra
Fulltext PDFPancytopenia is defined as a decrease in all three peripheral blood cell lines. A myriad of medications can cause pancytopenia. Daptomycin is a bactericidal antibiotic commonly used against gram-positive bacteria and has been increasingly used in treating Methicillin Staph aureus (MRSA). We present a case report of a 61-year-old male who was started on Daptomycin due to a soft tissue infection and subsequently developed pancytopenia. Pancytopenia did not initially improve by stopping the antibiotic or with colony-stimulating agents. However, blood counts did respond to trial of steroids, indicating a possible immune-mediated mechanism. This case report explores a rare, and possibly, novel adverse reaction to a commonly used antibiotic. Isolated reports of neutropenia and thrombocytopenia have been reported, but to our knowledge, this is the first case of Daptomycin-induced pancytopenia in the literature.
Daptomycin, Pancytopenia, Adverse Drug Reaction, Skin and Soft-Tissue Infections- SSTIs
Ratika Dogra, Jieshen Wu, Neeva Patel, Arlette Aouad. Case Report- Daptomycin Induced Pancytopenia and Review of Literature. Int Clinc Med Case Rep Jour. 2024;3(11):1-6.