International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 2, Issue 8 | Case Report | Open Access
Medical Student, B J Medical College, Ahmedabad, India
*Correspondence to: Rajvi ChaudharyFulltext PDF
JC virus, a human polyomavirus that is the etiologic agent of progressive multifocal leukoencephalopathy (PML), is an important opportunistic pathogen in patients with AIDS. PML is the only known clinical manifestation of JC virus infection. It is a late manifestation of AIDS and is seen in ~1–4% of patients with AIDS. PML is a lesion of the subcortical white matter of the brain and exhibits signs and symptoms according to involvement of multiple regions of the brain. Ataxia, hemiparesis, visual field defects, aphasia, and sensory defects may occur. Headache, fever, nausea, and vomiting are rarely seen.
We are presenting a case of a 32-year-old male patient who presented with slurring of speech, unilateral weakness, aphasia and difficulty in swallowing.
JCV; PML; Polyoma virus; Demyelination
Rajvi Chaudhary, Param Patel.Case Study: Progressive Multifocal Leukoencephalopathy Presenting as Early Manifestations of HIV. Int Clinc Med Case Rep Jour. 2023;2(8):1-7.