International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 2, Issue 17 | Case Report | Open Access DOI

Discussion of Disease Progression and Novel Treatment of Penile Mondor’s Disease

Dr. Iya Agha*

Iya Agha1*, Sarah Montaquila1, Ryan Cornell1, Sofia Barlas1, Saif Aldeen Agha2 and Ayad KM Agha2

1New York Institute of Technology College of Osteopathic Medicine-Old Westbury; Old Westbury, New York, USA

2IYA Medical; Scottsdale, Arizona, USA

*Correspondence to: Dr. Iya Agha 

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This case details the abnormal presentation, disease course, and definitive treatment of a patient suffering from Penile Mondor’s Disease (PMD) secondary to hypothesized hypercoagulable state due to a recent COVID-19 infection. This patient presented to the Interventional Radiology (IR) outpatient clinic after referral due to prolonged and inadequate treatment course of PMD. This patient was diagnosed with PMD after presenting with painful nocturnal erections that disrupted his quality of life through sexual dysfunction, inadequate sleep due to discomfort, painful daytime erections, and overall malpresentation. The patient failed two systemic treatments of systemic heparin after which was then referred to the IR clinic. The patient was treated definitively and experienced complete resolution of symptoms with catheter directed thrombolysis directly inside the affected superficial vein of the penis. The patient was treated in an outpatient setting and was seen at two weeks, one month, and two months follow up post-procedure without regression to previous disease state.


Interventional radiology; Minimally invasive; Outpatient procedure; Venous occlusion; Venous thrombosis; Penile mondor’s disease


Agha I, Montaquila S, Cornell R, Barlas S, Agha SA, Agha AKM. Discussion of Disease Progression and Novel Treatment of Penile Mondor’s Disease. Int Clinc Med Case Rep Jour. 2023;2(17):1-5.