International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 2, Issue 15 | Case Report | Open Access
Ramlah Khan BS*
Ramlah Khan BS1*, Saba Suleman MD2, Ahmed Abdelmonem MD2
1Texas A&M College of Medicine
2Internal Medicine, Baylor Scott & White All Saints, Fort Worth, USA
*Correspondence to: Ramlah Khan BS
Fulltext PDFDrug reaction with eosinophilia and systemic symptoms (DRESS) is a life-threatening drug-induced hypersensitivity syndrome that can present with a rash, facial edema, systemic symptoms, lymphadenopathy, visceral organ involvement, and eosinophilia. There is limited literature on DRESS syndrome following Chikungunya infection with concomitant sulfasalazine exposure. As fever and rash can present similarly in both DRESS syndrome and Chikungunya infection, the diagnosis can be quite challenging. Here, we present a patient who presented with fevers, facial swelling, intense pruritus, and a worsening morbilliform rash. Investigation revealed acute Chikungunya infection, leukocytosis, acute renal failure, and transaminitis. She was diagnosed with DRESS, and steroids were initiated, which prompted improvement in her symptoms. This report describes a case of DRESS following treatment for Chikungunya infection, a possibly novel trigger.
Drug reaction with eosinophilia and systemic symptoms (DRESS); Drug; Chikungunya
Ramlah Khan BS, Saba Suleman MD, Ahmed Abdelmonem MD. DRESS Syndrome following Sulfasalazine Treatment and Chikungunya Infection: A Case Report. Int Clinc Med Case Rep Jour. 2023;2(15):1-4.