International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 3, Issue 11 | Case Report | Open Access DOI

Dubin Johnson Syndrome and the Enigma Surrounding Conjugated Hyperbilirubinemia in Pregnancy: A Case Report

Jyotsna Shatrughan Dwivedi*

Shah DR1, Dwivedi JS1*, Nimbkar AR1 and Mali KA1

Department of Obstetrics and Gynaecology, Seth Gordhan Das Sunder Das Medical College and King Edward Memorial Hospital, India

*Correspondence to: Jyotsna Shatrughan Dwivedi 

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Abstract

1.1. Aim and Background: Jaundice in pregnancy is an uncommon condition. The aim is to diagnose a rare congenital hepatic disorder- Dubin Johnson Syndrome and elucidate an algorithm to arrive at it thus sensitizing the readers to unconventional diagnoses encountered while dealing with a case of jaundice in pregnancy.

1.2. Case Description: We present the case of a 27-year-old antenatal patient with unexplained conjugated hyperbilirubinemia exacerbating with every pregnancy in whom a set of comprehensive albeit feasible clinical tests helped to conclusively settle at the diagnosis of DJS.

1.3. Conclusion: More often benign than not, DJS is a rare entity with no risk of fibrosis progression, cirrhosis or adverse perinatal outcomes.

1.4. Clinical Significance: It is imperative to diagnose DJS not only to differentiate it from other pre-existing or concurrent hepatic disorders in pregnancy considerably impacting management strategies and foetal-maternal outcomes but also to reassure the patient of its benign course, an essential element of good clinical practice.

Keywords:

Dubin johnson syndrome; Jaundice in pregnancy; Liver disease in pregnancy; Hyperbilirubinemia; Case report

Citation:

Shah DR, Dwivedi JS, Nimbkar AR, Mali KA. Dubin Johnson Syndrome and the Enigma Surrounding Conjugated Hyperbilirubinemia in Pregnancy: A Case Report. Int Clinc Med Case Rep Jour. 2024;3(11):1-5.