International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 4, Issue 6 | Research Article | Open Access DOI
Bhushan Chauhan*
Bhushan Chauhan1*, Komal Chauhan2
1ENT, Maharishi Markandeshwar (Deemed to be University), located in Mullana, Ambala, India
2Department of Food Science and Technology, National Institutre of Food Technology Entrepreneurship and Management, Kundli, Sonepat, 131028, India
*Correspondence to: Bhushan Chauhan
Fulltext PDFThe study has been conducted to assess the effect of anti-reflux medication in patients with clinical manifestations of laryngopharyngeal reflux and non-allergic rhinitis. Patients were screened for NAR and LPR using nasal endoscopy, Total Nasal Symptom Score (TNSS), Reflux Symptom Index (RSI) and Reflux Finding Score (RFS). The selected patients were randomly divided into control (n=34) and treated (n=38) groups and the therapeutic protocol involved a three-month course of anti-reflux medication with periodic assessments at 0, 4, 8, and 12 weeks. The control and treated groups received starch (20mg) and omeprazole (20mg) capsules, twice a day respectively. The patients were evaluated for TNSS, RSI and RFS periodically. The results indicated a decreasing trend in TNSS (10±0.14 - 3±0.11) and marked (p≤0.05) improvement in LPR symptoms in the treated group for nasal parameters, while the control group showed no significant change (p≥0.05) in TNSS (9.81±0.12 - 9.68±0.14) and LPR symptoms. Likewise, the RSI and RFS scores demonstrated a decreasing trend in the treated group, with a significant (p≤0.05) decrease at 12th week. The post supplementation, RSI and RFS scores in the treated group showed a substantial percent decrease (-58.4% and -50% respectively) indicating positive effects of omeprazole in counteracting LPR manifestations. The study provides evidence supporting the efficacy of anti-reflux medication in alleviating LPR symptoms in patients with non-allergic rhinitis. The positive impact on TNSS, RSI, and RFS scores highlights the potential of anti-reflux therapy as a viable treatment option for individuals with interconnected upper airway conditions.
Total Nasal Symptom Score; Rhinorrhea, Reflux Symptom Index; Reflux Finding Score; Non-Allergic Rhinitis; Laryngopharyngeal Reflux
Bhushan Chauhan, Komal Chauhan. Effect of Anti Reflux Medication in Patients with Laryngopharyngeal Reflux and Non-Allergic Rhinitis. Int Clinc Med Case Rep Jour. 2025;4(6):1-3.