International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 5, Issue 2 | Research Article | Open Access
Yuping Zhu & Guiyu Wang*
Jun Luo1,2#, Zitong Wang1#, Jing Lai6#, Meijuan Zhu3, Yong Liu2, Zhibin Fang5, Chaojing Zheng4, Yunxiao Liu1, Chunlin Wang1, Qian Zhang2, Nana Zhang1, Meng Wang2, Haiyang Feng2, Yuping Zhu2*，Guiyu Wang1*
1Department of Colorectal Tumor Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150086, Heilongjiang, China
2Department of Colorectal Cancer Surgery, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, China
3Department of Clinical Psychology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022, China
4Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, Fujian , China
5Postgraduate Training Base Alliance of Wenzhou Medical University, Hangzhou, Zhejiang 310022, China
6People's Hospital of Kecheng District, Quzhou, Zhejiang 324000, China
#Jun Luo, Zitong Wang, Jing Lai contributed equally to this work
*Correspondence to: Yuping Zhu & Guiyu Wang
Fulltext PDFPurpose: This study aimed to compare the perioperative and survival outcomes of elective colorectal cancer resection performed during daytime versus nighttime hours to determine if nighttime surgery yields comparable results.
Methods: We retrospectively reviewed the clinical data of 265 patients, categorizing them into nighttime or daytime groups based on surgery start and end times. Baseline characteristics were compared. Risk factors for perioperative complications, progression-free survival (PFS), and overall survival (OS) were analyzed, along with PFS and OS between groups.
Results: The median follow-up was 46 months (range: 0–48). Of the 265 patients, 69 (26.0%) underwent nighttime surgery. No significant differences were observed in baseline characteristics or perioperative outcomes between groups (P > 0.05). Adjusted logistic regression identified a primary lesion diameter ≥50 mm as an independent risk factor for perioperative complications (OR: 2.24, 95% CI: 1.09–4.60). Timing of surgery was not significantly associated with complications (OR: 0.99, 95% CI: 0.53–1.85). Nighttime surgery did not significantly affect PFS (HR = 1.00, 95% CI: 0.55–1.82, P = 0.995) or OS (HR = 0.63, 95% CI: 0.27–1.45, P = 0.277).
Conclusion: Nighttime elective colorectal cancer resection demonstrates similar short-term safety and long-term survival outcomes compared to daytime surgery. Nighttime surgery may be considered when daytime operating capacity is insufficient.
Nighttime surgery; Colorectal cancer; Short-term outcomes; Survival
Jun Luo, Zitong Wang, Jing Lai, Meijuan Zhu, Yong Liu, Zhibin Fang, Chaojing Zheng, Yunxiao Liu1, Chunlin Wang, Qian Zhang, Nana Zhang, Meng Wang, Haiyang Feng, Yuping Zhu，Guiyu Wang. Elective Colorectal Cancer Resection during Nighttime Hours is Clinically Acceptable. Int Clinc Med Case Rep Jour. 2026;5(2):1-16.