International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 3, Issue 5 | Case Series | Open Access DOI
Muhammad Ahmad Qureshi*
Muhammad Ahmad Qureshi1, Omair Ahmed3, Haseeb Khan Tareen1*, Anza Muhammad1, Faiza Khan1, Affaf Shahid2, Muiz Khan Tareen2, Minahil Fatima1, Furqan Yaqub Pannu1, Hafsa Ahmed4
1King Edward Medical University, Nila Gumbad Chowk, Anarkali, Lahore, Pakisthan
2Allama Iqbal Medical College, Main Jinnah Hospital, Lahore, Pakisthan
3Henry Ford Jackson Hospital, 205 N East Ave, Jackson, MI 49201
4Sheikh Zayed Medical College and Hospital, Rahim Yar Khan, Pakisthan
*Correspondence to: Muhammad Ahmad Qureshi
Fulltext PDFIntroduction and Background: Cardiac myxomas are rare tumors that present a complex clinical spectrum, leading to a challenging diagnosis. In this retrospective study, we explore the clinical manifestations, diagnostic complexities, and surgical outcomes of cardiac myxomas.
Methods: A retrospective analysis of 10 patients diagnosed with cardiac from 2018 to 2023 was conducted. Clinical records including age, gender, tumor dimensions, and symptoms were reviewed. Data were analyzed using descriptive statistics and SPSS V23.0.0 software.
Results: The median age of patients was 48.5 years, having a slight male predominance (60%). Cardiac symptoms were observed in 70% of the patients. These included dyspnea, palpitations, fatigue, syncope, and heart failure. Neurologic symptoms were present in 20%, while constitutional symptoms such as fever, weight loss, and fatigue affected 70% of patients. Myxomas were primarily located in the left atrium (70%), followed by the right atrium (20%) and left ventricle (10%). Echocardiography and histopathological evaluation confirmed diagnoses. All patients underwent successful surgical excision with no major complications.
Discussion: Our findings align with previous studies regarding age distribution and gender prevalence. Cardiac myxomas exhibit a diverse range of symptoms, making diagnosis challenging. Constitutional symptoms are frequently observed and may result from elevated interleukin-6 levels. Diagnostic tools such as echocardiography and histopathology play pivotal roles in confirming myxoma diagnoses. Surgical excision remains the gold standard treatment, ensuring positive outcomes.
Conclusion: Cardiac myxomas present with a myriad of clinical manifestations, necessitating a high index of suspicion for accurate diagnosis. This retrospective case series underscores the importance of prompt surgical intervention following diagnosis, offering favorable outcomes and a resolution of symptoms. Further studies are needed to explore the underlying pathophysiological mechanisms of cardiac myxomas and their systemic effects.
Cardiac myxomas; Tumors
Muhammad Ahmad Qureshi, Omair Ahmed, Haseeb Khan Tareen, Anza Muhammad, Faiza Khan, Affaf Shahid, et al. Exploring the Clinical Spectrum, Diagnosis, and Outcomes of Cardiac Myxomas: A Comprehensive Retrospective Case Series. Int Clinc Med Case Rep Jour. 2024;3(5):1-10.