International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 4, Issue 9 | Case Report | Open Access
Bashir Abdrhman Bashir*
Department of Hematology, Faculty of Medical Laboratory Sciences, Port Sudan Ahlia University, Sudan
*Correspondence to: Bashir Abdrhman Bashir
Fulltext PDFBackground: Hairy Cell Leukemia (HCL) is an uncommon, indolent B-cell lymphoproliferative illness distinguished by unique cytological characteristics and a generally subtle clinical progression.
Case presentation: We present the case of an 85-year-old Sudanese man exhibiting prominent pancytopenia, splenomegaly, and recurrent infections. A peripheral blood smear showed lymphoid cells with cytoplasmic projections, and a bone marrow biopsy revealed diffuse infiltration with lymphocytes that resembled "fried eggs." The lack of flow cytometry and cytogenetic analysis, due to infrastructural constraints intensified by ongoing armed conflict, highlights the essential need for clinical expertise and morphological observation in resource-limited settings.
Conclusion: The above scenario highlights the importance of maintaining a high clinical suspicion for HCL in pancytopenic patients, particularly in resource-constrained environments. It highlights the importance of immunophenotypic validation to ensure accurate diagnosis and inform treatment decisions.
Hairy cell leukemia, B-cell; Lymphoproliferative disease; Lymphocytes projection; Sudan
Bashir Abdrhman Bashir. Hairy Cell Leukemia in Sudan: A Case Highlighting Morphological Diagnosis Under Resource Constraints. Int Clinc Med Case Rep Jour. 2025;4(9):1-6.