International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 4, Issue 3 | Case Report | Open Access DOI

Incomplete Lemierre Syndrome: A Fusobacterium Induced Sepsis in a Middle-Aged Male

Sohair Angly MD*

Sahar S. Abdelmoneim, M.D., M.B.A., Ingy Farag DO, Angelica Perez Fonte MS III, David Romero-Fischmann MD, Sohair Angly MD*

Division of Internal Medicine, Larkin Palm Springs Community Hospital, and Larkin South Miami, Florida. Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Florida

*Correspondence to: Sohair Angly MD 

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Abstract

Lemierre syndrome (LS) is a rare, life-threatening condition characterized by septic thrombophlebitis of the internal jugular vein (IJV), typically following an oropharyngeal infection with Fusobacterium necrophorum. We present a previously healthy 41-year-old male who developed Fusobacterium-induced sepsis without radiologically confirmed internal jugular vein thrombosis. The patient presented with altered mental status, systemic inflammatory response, and right upper extremity edema. Imaging revealed multiple bilateral pulmonary nodules and subcutaneous emphysema. Despite the absence of radiologically confirmed IJV thrombosis, blood and wound cultures confirmed F. necrophorum infection, establishing the diagnosis of LS. The patient required intensive care, broad-spectrum antibiotics, and surgical intervention, ultimately recovering with targeted antimicrobial therapy. This case highlights an atypical “incomplete” LS presentation, emphasizing the need for high clinical suspicion, early diagnosis, and prompt treatment to reduce morbidity and mortality.

Keywords:

Lemierre syndrome; Fusobacterium necrophorum; Septic thrombophlebitis; Internal jugular vein thrombosis; Oropharyngeal infection; Septicemia; Atypical Lemierre syndrome; Septicaemia

Citation:

Sahar S. Abdelmoneim, M.D., M.B.A., Ingy Farag DO, Angelica Perez Fonte MS III, David Romero-Fischmann MD, Sohair Angly MD. Incomplete Lemierre Syndrome: A Fusobacterium Induced Sepsis in a Middle-Aged Male. Int Clinc Med Case Rep Jour. 2025;4(3):1-5.