International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 4, Issue 4 | Research Article | Open Access DOI
Prof. Dr. Dr. Hüseyin NAZLIKUL*
Hüseyin NAZLIKUL1,2,3, Fatma Gülcin URAL NAZLIKUL4,5, Mehmet Dincer BILGIN6,7, Tijen ACARKAN8 , Neslihan ÖZKAN9 and Yusuf TAMAM10,11*
1 President of IFMANT (International Federation of Medical Associations of Neural Therapy), Schattenhalb, Switzerland
2 President of the Turkish Neural Therapy Society (BNR), Istanbul, Turkey
3 Specialist in General Medicine, Pain Medicine, PMR and Medical Biophysics and Private practice at the Natural Health Clinic, Istanbul, Turkey
4 Department of Physical Medicine and Rehabilitation, Istanbul Health and Technology University, Istanbul, Turkey
5President of the Association for Scientific Complementary Medicine and Regulation (BTR), Istanbul, Turkey
6Aydın Adnan Menderes University Graduate School of Health Sciences, Department of Biophysics, Aydın, Turkey
7Aydın Adnan Menderes University Faculty of Medicine, Department of Biophysics, Aydın, Turkey
8 Independent Physician, Istanbul, Turkey
9 Independent Physician, Physiotherapist (PRM), Bursa, Turkey
10 University Of Health Sciences, Adana City Health Practice and Research Centre, Department of Internal Medicine / Department of Neurology, Turkey
11 President of Asia-Europe Federation of Medical Regulation, Istanbul, Turkey
*Correspondence to: Prof. Dr. Dr. Hüseyin NAZLIKUL
Fulltext PDFBackground: Migraine is one of the most common neurological disorders and significantly impairs quality of life. While conventional therapies may alleviate symptoms, they often fail to address the underlying causes. Neural therapy is a therapeutic approach in which local anesthetics such as procaine or lidocaine are not primarily used for analgesia but rather to modulate the autonomic nervous system, particularly its sympathetic branch. This method aims to restore functional balance and stabilize dysregulated networks through segmental and systemic reflex pathways, thereby supporting a holistic regulatory effect.
Objective: This retrospective study aims to evaluate the effectiveness of neural therapy in 464 migraine patients using a holistic, regulatory medical approach.
Methods: Patient history forms were analyzed for hormonal dysregulation, intestinal dysbiosis, temporomandibular dysfunction, C2 vertebral blockage, hydration status, and interference fields. Additionally, clinical treatment progressions were statistically assessed.
Results: Over 91% of patients demonstrated clinical improvement, and 60% became symptom-free. The most frequently observed contributing factors were intestinal dysbiosis (89%), hormonal imbalance (71%), and temporomandibular/C2 dysfunctions (43% each).
Conclusion: Neural therapy is an effective and regulatory therapeutic option for migraines, particularly in chronic, multifactorial cases. Its integration into a holistic treatment strategy may yield substantial clinical benefits.
Neural therapy; Autonomic nervous system; Local anaesthetic (Procaine, Lidocaine); Migraine; Regulatory approach
H. NAZLIKUL, F.G. URAL NAZLIKUL, M.D. BILGIN, T. ACARKAN, N. ÖZKAN, Y. TAMAM. Neural Therapy in Migraine: Clinical Evidence for a Holistic Therapeutic Approach – Analysis of 464 Cases. IntClinc Med Case Rep Jour. 2025;4(4):1-7