International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 4, Issue 11 | Clinical Image | Open Access DOI

Oral and Esophageal Candida Infection in a Patient with Chronic Mucocutaneous Candidiasis and White Sponge Nevus

Qasim Abbas*

Qasim Abbas*, Mohamed A. Alhajajy, Mohamad Alnassar

Department of Internal Medicine, GI-unit, Sultan Qaboos University Hospital, Muscat, Oman

*Correspondence to: Qasim Abbas 

Fulltext PDF

Abstract

A 22-year-old woman with chronic mucocutaneous candidiasis (CMC), white sponge nevus syndrome, and a homozygous KRT14 gene mutation, who was referred to gastroenterology for persistent dysphagia. She has 2 brothers with similar disease.

The first image (Figure 1) shows the patient's tongue, which exhibits thick, white plaques characteristic of Candida infection, a hallmark of CMC. These lesions are persistent and recurrent, often found in individuals with an underlying genetic predisposition to chronic mucosal infections.

The patient underwent an esophagogastroduodenoscopy (OGD) due to her dysphagia. The second image (Figure 2) shows an endoscopic view of the esophagus, revealing diffuse white plaques along the mucosa. These plaques are typical of Candida esophagitis, which is commonly seen in immunocompromised patients or those with underlying genetic conditions like CMC. Histopathology of biopsy samples from the esophagus confirmed Candida esophagitis.

Keywords:

Citation:

Qasim Abbas, Mohamed A. Alhajajy, Mohamad Alnassar. Oral and Esophageal Candida Infection in a Patient with Chronic Mucocutaneous Candidiasis and White Sponge Nevus. Int Clinc Med Case Rep Jour. 2025;4(11):1-2.