International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 1, Issue 1 | Case Report | Open Access

Paraneoplastic Limbic Encephalitis – A Case Report

Rawan Alshammari*

Department of Neurology, Department of Intensive Care Unit, AL-Adan Hospital – Kuwait

*Correspondence to: Rawan Alshammari 

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We present a case of Anti NMDAR encephalitis with ovarian teratoma, describing the presenting features, diagnosis and management plan.

Early Electroencephalography showed typical features of Anti NMDAR encephalitis which promoted the early diagnosis of ovarian teratoma and immediate surgical removal.

All approved treatment failed but finally improved with ocrelizumab.


Anti-N-methyl-D-aspartate receptor encephalitis is a paraneoplastic syndrome which is invariably related to cancer, as ovarian teratoma; patient typically will have a range of symptoms as, memory deficits, seizures, decrease level of consciousness , dyskinesia , autonomic instability as hyperthermia, fluctuations of BP, cardiac problems, rigidity, sometimes hypoventilation that require mechanical ventilation and need ICU admission. Anti – NMDAR encephalitis that associated with teratoma is life threating conditions that need multidisciplinary care and immediate surgical removal.

Case Report

We presented a case of a young girl who had a symptoms of viral illness , then developed psychological symptoms and then went into status epilepticus.

She was admitted to the ICU and was diagnosed with paraneoplastic encephalitis related to ovarian teratoma.

The patient received all the treatment options and surgical removal of the tumor was done.


Ocrelizumab showed a great improvement when all other treatment options failed.

EEG can help for early diagnosis and management of the case.


Limb; Ovarian; Cardiac; surgery


Rawan Alshammari, Talal Alenezi, Ponnusamy Santhamoorthy, Beena Yousef Omar Balmasoud, Mohammad Shamshah ,Huda Alfodari , Mishal Abu Almelh. Paraneoplastic Limbic Encephalitis – A Case Report. Int Clinc Med Case Rep Jour. 2022;1(1):1-7.