International Clinical and Medical Case Reports Journal (ISSN: 2832-5788) | Volume 2, Issue 17 | Case Report | Open Access DOI
Dorian Laslo*
Dorian Laslo1*, Ivana Franić Šimić2, Vlatka Periša1,3
1Faculty of Medicine Osijek, University Josip Juraj Strossmayer Osijek, Osijek, Croatia
2Cinical Hospital Centre Osijek, Clinic of Internal medicine, Department of haematology, Osijek, Croatia
3Clinical Hospital Centre Zagreb, Clinical department for laboratory diagnostics, Zagreb, Croatia
*Correspondence to: Dorian Laslo
Fulltext PDFChronic myeloid leukemia (CML) is clonal disorder characterised by reciprocal translocation t(9, 22). About half of the patients are asymptomatic. Unilateral vision disturbance is very rare symptom of CML and we present the second case report. A 34-year-old, previously healthy, man presented with complaints of blurring in right eye. The visual acuity was 0.5 in the right eye, with normal vision on the left. Intraretinal hemorrhage in the right eye was confirmed by fundoscopy and optical coherence tomography. A hemogram showed a total leukocyte count of 178,3 x10^9/L. He had a splenomegaly without other bleeding manifestations. Cytogenetics revealed a karyotype of 46, XY, t (9;22). FISH analysis proved Philadelphia chromosome in 96% of cells and the patient was diagnosed as CML and started imatinib therapy. All patients presented with retinal bleeding wihtout clear reason should performe blood tests, because it is the only way to rule out CML.
BCR-ABL Positive chronic myelogenous leukemia; Imatinib mesylate; Retinal hemorrhage; Vision disorders
Dorian Laslo, Ivana Franić Šimić, Vlatka Periša. Unusual Retinal Hemorrhages as A First Sign of Chronic Myeloid Leukemia: A Case Report. Int Clinc Med Case Rep Jour. 2023;2(17):1-5.