Annals of Otolaryngology Head and Neck Surgery (ISSN 2835-7132) | Volume 5, Issue 4 | Case Report | Open Access

Novel Application of Platelet-Rich Plasma (PRP) Therapy in Treating Atrophic Rhinitis: A Regenerative Perspective for a Challenging Nasal Disease

Mostafa Kamal Arefin*

Mostafa Kamal Arefin1 and Ashraful Islam2

1ENT Specialist & Consultant, Popular Medical College & Hospital, Dhaka, Bangladesh

2Professor and ex -HOD, Department of ENT, Bangladesh Medical College & Hospital, Bangladesh

*Correspondence to: Mostafa Kamal Arefin 

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Abstract

Atrophic rhinitis (AR) is a chronic debilitating nasal disorder characterized by progressive mucosal atrophy, crust formation, fetor, nasal dryness, and impaired mucociliary clearance. Conventional treatment remains largely palliative and often fails to restore normal nasal physiology. Recently, platelet-rich plasma (PRP), an autologous concentrate rich in growth factors and cytokines, has emerged as a promising regenerative modality in different fields of otorhinolaryngology. Preliminary studies suggest that PRP injection may improve nasal mucosal regeneration, vascularity, mucociliary function, and patient symptoms in atrophic rhinitis. This short communication highlights the possible mechanisms, clinical potential, advantages, limitations, and future directions of PRP therapy in the management of atrophic rhinitis.

Keywords:

Atrophic rhinitis; Platelet-rich plasma; PRP; Regenerative therapy; Nasal mucosa; Mucociliary clearance; Rhinology

Citation:

Mostafa Kamal Arefin and Ashraful Islam. 1ENT Specialist & Consultant, Popular Medical College & Hospital, Dhaka, Bangladesh. Annal of Otol Head and Neck Surg. 2026;5(4):1-5.