Annals of Otolaryngology Head and Neck Surgery (ISSN 2835-7132) | Volume 3, Issue 5 | Research Article | Open Access
Paroma Mukherjee*
1Department of Otorhinolaryngology, NRS Medical College & Hospital, India
2Department of Otorhinolaryngology, NRS Medical College & Hospital, India
3Department of Otorhinolaryngology, India
4Department of Otorhinolaryngology, NRS Medical College & Hospital, India
5Department of Otorhinolaryngology, NRS Medical College & Hospital, India
6Department of Otorhinolaryngology, NRS Medical College & Hospital, India
*Correspondence to: Paroma Mukherjee
Fulltext PDFIntroduction: This study attempts to see the role of weekly Intratympanic injection of Dexamethasone in the management of patients with idiopathic subjective tinnitus in a tertiary care hospital in Kolkata, West Bengal, India. Objective assessment was done by noting the change in Pure Tone Audiometry (PTA) & subjective analysis by Tinnitus Handicap Inventory (THI) score sequentially on Day 1, 4th week, 6th week, 8th week and 12th week.
Methods: 55 patients aged between 18 years to 65 years with idiopathic subjective tinnitus were enrolled in our study and 0.5 ml of intratympanic dexamethasone was administered in the respective ear under microscopic vision for 8 weeks. Changes in the THI & PTA were recorded on Day 1, week 4, week 6, week 8 & week 12 respectively.
Results: Based on PTA reports & THI, at the end of 12 weeks, improvement in symptoms was noted in 38 patients (69.09%), 12 patients (21.82%) did not show appreciable improvement over time, 2(3.64%) patients left the study midway due to lack of improvement in symptoms and 3(5.45%) patients were lost to follow-up. On comparing THI at Day 1 & week 12, a p-value of <0.0001 was obtained.
Conclusion: The p-value based on THI change from Day 1 to week 12 is <0.0001 which is statistically significant. An improvement in the grade of tinnitus based on THI & PTA was noted at week 12. Thus, we can conclude that Intratympanic Injection of Dexamethasone plays a pivotal role in managing idiopathic subjective tinnitus.
Tinnitus, Intratympanic Dexamethasone; Tinnitus Handicap Inventory; Pure Tone Audiometry
Paroma Mukherjee, Pranabashish Banerjee, Kanishka Chowdhury, Kahkasha Alam, Trailokeswar Prusti, Ayan Biswas. Role of Intratympanic Dexamethasone in The Management of Tinnitus- Our Experience. Annal of Otol Head and Neck Surg. 2024;3(5):1-8.